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Keynote Lecture

WEB Hydrophobic Interactions in Soft Matter



The vast majority of biological molecules (proteins, lipids, etc.) are amphiphilic, indeed often their water interface presents hydrophobic and hydrophilic patches coexisting at a molecular scale. In light of this observation, in my talk, I will show how amphiphilic nanomaterials (nanoparticles and macromolecules) can establish a series of unique interactions with biological materials. Particular attention will be dedicated to discussing the role and the nature of hydrophobic interaction, highlighting what we do and do not understand about them. Novel approaching to quantify these interactions will be presented and considerations on how to strengthen or mitigate them will be discussed. In particular, we will discuss the methods used to characterize the nanoparticles and the interactions.

Speaker:
Prof. Francesco Stellacci
Ecole Polytechnique Fédérale de Lausanne